Hypothyroidism Preceding Hyperthyroidism in a Patient with Continuously Positive Thyroid Stimulating Antibody.
نویسندگان
چکیده
منابع مشابه
Thyroid-stimulating antibody in a patient with euthyroid Graves' disease.
We report an 11-year-old girl with euthyroid Graves' disease. She was referred to our clinic because of left exophthalmos without other symptoms suggestive of hyperthyroidism. Her serum concentration of free thyroxine (FT4) and free triiodothyronine (FT3) were normal, but thyroid-stimulating hormone (TSH) was below normal and impaired TSH response to TSH releasing hormone (TRH) was found. Altho...
متن کاملA monoclonal thyroid-stimulating antibody.
The thyrotropin receptor, also known as the thyroid-stimulating hormone receptor (TSHR), is the primary antigen of Graves disease. Stimulating TSHR antibodies are the cause of thyroid overstimulation and were originally called long-acting thyroid stimulators due to their prolonged action. Here we report the successful cloning and characterization of a monoclonal antibody (MS-1) with TSHR-stimul...
متن کاملA Case of a False-Positive Anti-Myeloperoxidase Antibody ELISA in a Patient with Hypothyroidism
We present a case of a false-positive anti-myeloperoxidase (MPO) antibody result on an ELISA in a patient with anti-thyroid microsomal antibody (TMA)-positive hypothyroidism. A 41-year-old woman presented with dyspnea on exertion. The initial evaluation revealed pericardial effusion associated with hypothyroidism. In addition, microscopic hematuria with normal renal function and positive cytopl...
متن کاملThyroid-stimulating Antibody Activity
To investigate the distribution of thyroid-stimulating antibody (TSAb) activity between IgG subclasses, sera from 11 patients with Graves disease (including the National Institute of Biological Standards and Control (NIBSC) Research Standard, long acting thyroid stimulator-B) were fractionated by chromatography on affinity columns of monoclonal IgG subclass antibodies or protein A to deplete al...
متن کاملRelationship between thyroid stimulating hormone and thyroid stimulating immunoglobulin in Graves' hyperthyroidism.
BACKGROUND AND AIM In Graves' hyperthyroidism, suppression of serum TSH after restoration of normal serum T4 and T3 with treatment has been attributed to binding of TSH-receptor antibodies to TSH receptors in the pituitary. Accordingly, the relationship between TSH and serum thyroid stimulating immunoglobulin (TSI) was examined during follow-up of patients with Graves' hyperthyroidism. SUBJEC...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 1995
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.34.247